People who develop neuromyelitis optica spectrum disorder (NMOSD) at an older age are more likely to experience spinal cord inflammation and less likely to have eye nerve involvement, not only in the first attack but also in subsequent relapses, a study has found. In addition, data show “different relapse…
Disease progression
People with neuromyelitis optica spectrum disorder (NMOSD) who switch between treatments more than once because of side effects or non-medical reasons have an increased risk of disease activity, a study shows. While each additional switch for either reason increased the risk of NMOSD activity, no such association was seen…
Blood levels of prolactin, a hormone mostly known for its role in milk production, are significantly elevated in people with neuromyelitis optica spectrum disorder (NMOSD) as compared with healthy adults, a study found. Among NMOSD patients, these high prolactin levels were significantly associated with active disease, sensory-related symptoms, and…
People with neuromyelitis optica spectrum disorder (NMOSD) experience faster disability progression with fewer attacks than those with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), a related condition, according to a long-term analysis of German registry data. Notably, in all patients, experiencing inflammation in the optic nerve, which transmits signals between…
Nearly 1 in 5 people with neuromyelitis optica spectrum disorder (NMOSD) experience early neurological symptoms prior to their first established NMOSD attack, new research suggests. These symptoms could represent an NMOSD prodrome, a disease stage where nonspecific symptoms emerge before the classic manifestations of the disease. A better…
Problems in the autonomic nervous system (ANS), which regulates involuntary bodily processes such as heart rate, blood pressure, and digestion, are very frequent among people with neuromyelitis optica spectrum disorder (NMOSD), a study has shown. All 80 NMOSD patients in the study experienced ANS-related symptoms, and a greater burden…
The clinical symptoms of neuromyelitis optica spectrum disorder (NMOSD) in people in their 50s or older may look like those of a stroke — which can delay proper diagnosis and treatment of the the progressive autoimmune disorder, according to a case report and systematic literature review. That’s what happened…
Neuromyelitis optica spectrum disorder (NMOSD) is associated with a faster loss of white matter volume in the brain, but taking the corticosteroid prednisolone may help counter this effect, according to a small study in Japan. The brain’s white matter contains the long, wire-like projections, or fibers, that nerves use…
A history of smoking is associated with poorer recovery from disease relapses in people with neuromyelitis optica spectrum disorder (NMOSD), a study reports. Findings indicate that patients who smoke or are past smokers are more likely to have neurological lesions that persist months after the relapse, and that these…
Nearly two in 10 neuromyelitis optica spectrum disorder (NMOSD) patients develop new asymptomatic brain and spinal cord lesions during the period of disease remission, but these do not appear to increase risk of relapse, according to a study in Argentina. Asymptomatic, or silent, lesions are those that can be…
Recent Posts
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