diagnosis

A chemotherapy regimen was able to treat a woman’s neuromyelitis optica spectrum disorder (NMOSD) which was likely secondary to follicular lymphoma, a type of cancer that begins in cells of the immune system, according to a case report by researchers at King’s College London in the U.K. O-CVP —…

Researchers have identified a rare case of co-existing neuromyelitis optica spectrum disorder (NMOSD) and subacute combined degeneration (SCD) — two distinct disorders marked by nerve damage in the brain or spinal cord. The case highlights the possibility that NMOSD may be the underlying driver of the vitamin B12 deficiency…

Adults with neuromyelitis optica spectrum disease (NMOSD) who are positive for antibodies against the aquaporin-4 (AQP4) protein have a higher prevalence of oval-shaped masses surrounding the optic nerve in their eyes than healthy people, a study showed. Although these masses were significantly linked to older age, their occurrence was…

Certain variations in the ESR1 gene — a protein-coding gene for estrogen receptor-alpha — are significantly more common among women with neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis (MS) than among healthy women, a small study suggests. Such differences were not observed between men with these…

Brain age gap (BAG) — the difference between calendar age and predicted brain age as determined by MRI scans — was significant in adults with neuromyelitis optica spectrum disorder (NMOSD), and may predict disability in patients, a study found. The BAG was even greater in people with the related…

Measuring the retinal nerve layers by a non-invasive tool called optical coherence tomography may help to diagnose neuromyelitis optica spectrum disorder (NMOSD), especially in those who test negative for disease-related antibodies, according to a new study. Researchers found that nerve layers in the retina of people with NMOSD…

It feels like there’s a test for everything. As I hit milestones with neuromyelitis optica (NMO), a rare autoimmune disease that can affect the spinal cord and optic nerves, I am subjected to more tests. The latest was a bone density test, also called a dual-energy X-ray absorptiometry (DEXA)…

Reaching a neuromyelitis optica spectrum disorder (NMOSD) diagnosis in the absence of disease-causing antibodies requires careful attention from physicians in order to ensure timely treatment. That suggestion comes from a case report of a man in Nepal who had symptoms of the autoimmune disease but lacked the antibodies against…

Older age, diagnostic delays, and a greater disability at diagnosis were associated with a higher risk of developing permanent disability for people with neuromyelitis optica spectrum disorder (NMOSD) at a center in Mexico. “This information is required to design healthcare strategies to recognize and treat patients with NMOSD early…

Impairments in the visual field — the total area in which objects can be seen in a person’s peripheral vision — were found in adults with optic neuritis (ON) related to neuromyelitis optica spectrum disorder (NMOSD), according to a new study. NMOSD patients with optic neuritis had more visual…