neutrophils

NLR immune cell ratio may be NMOSD inflammation biomarker

People with neuromyelitis optica spectrum disorder (NMOSD) have a significantly higher neutrophil-to-lymphocyte ratio (NLR), an immune cell-based marker of inflammation, than healthy people, a review study showed. A higher NLR ratio was also significantly associated with a greater chance of relapse, severe disability, and new or enlarging lesions on…

Inflammatory Neutrophils Resist Cell Death in AQP4 + NMOSD: Study

Neutrophils, a set of immune cells, from people with aquaporin-4 (AQP4) antibody-positive neuromyelitis optica spectrum disorder (NMOSD) are resistant to certain forms of cell death, a study found. NMOSD patients also had increased blood levels of molecules that might help neutrophils resist cell death pathways. Similar findings weren’t observed…