misdiagnosis

Misdiagnoses common in patients with first symptoms in brainstem

Neuromyelitis optica spectrum disorder (NMOSD) patients whose first symptoms affect the brainstem, which is the bottommost part of the brain, are frequently misdiagnosed and experience higher rates of relapses, according to a two-center study in China. Data also showed about half of these patients initially experienced uncontrollable nausea, vomiting,…

Symptoms like a stroke may be seen in NMOSD patients over 50

The clinical symptoms of neuromyelitis optica spectrum disorder (NMOSD) in people in their 50s or older may look like those of a stroke — which can delay proper diagnosis and treatment of the the progressive autoimmune disorder, according to a case report and systematic literature review. That’s what happened…

Brain Inflammation May Complicate NMOSD Diagnosis

A specific pattern of brain inflammation called BPCLI sometimes can occur in people with neuromyelitis optica spectrum disorder (NMOSD), and often is associated with encephalitis-like symptoms that may contribute to misdiagnoses. A study with that finding, “Bilateral parafalcine cortical and leptomeningeal impairment: A characteristic pattern of MOG antibody…