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June 6, 2025 News by Marisa Wexler, MS

Study IDs 4 proteins as potential drug targets for treating NMOSD

High levels of two proteins, called FAM3B and PF4V1, are associated with a reduced risk of neuromyelitis optica spectrum disorder (NMOSD), while elevated levels of two other proteins, called CLEC11A and SERPINA1, are linked to increased odds of developing the immune system disease. These are the findings of a…

June 6, 2023 News by Lindsey Shapiro, PhD

Signaling protein CCL2 may promote nerve damage in NMOSD: Study

CCL2, a signaling protein that recruits immune cells to sites of injury, may play a key role in driving the nerve damage that results from antibodies against the aquaporin-4 (AQP4) protein in neuromyelitis optica spectrum disorder (NMOSD), a study suggests. The signaling protein was found to be elevated in…

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