The clinical symptoms of neuromyelitis optica spectrum disorder (NMOSD) in people in their 50s or older may look like those of a stroke — which can delay proper diagnosis and treatment of the the progressive autoimmune disorder, according to a case report and systematic literature review. That’s what happened…
case report
Neuromyelitis optica spectrum disorder (NMOSD) may begin to manifest as uncontrollable nausea, vomiting, or hiccups — a condition referred to as area postrema syndrome (APS) — as described in a report of four patients in China. Because these symptoms can overlap with those of other diseases, their occurrence…
A chemotherapy regimen was able to treat a woman’s neuromyelitis optica spectrum disorder (NMOSD) which was likely secondary to follicular lymphoma, a type of cancer that begins in cells of the immune system, according to a case report by researchers at King’s College London in the U.K. O-CVP —…
In rare cases, people with neuromyelitis optica spectrum disorder (NMOSD) can experience low blood levels of neutrophils, a type of immune cell, a few weeks after receiving anti-CD20 therapy. Researchers have reported the case of a NMOSD patient who developed the uncommon side effect, called late-onset neutropenia, four…
The CoronaVac vaccine, which contains inactivated SARS-CoV-2, the virus that causes COVID-19, led to a severe case of late-onset neuromyelitis optica spectrum disorder (NMOSD) in a 70-year-old woman. The unique case was described in an article, “Fulminant neuromyelitis optica spectrum disorder (NMOSD) following COVID-19 vaccination: A…
A man’s first manifestation of neuromyelitis optica spectrum disorder (NMOSD) was aseptic meningitis, an inflammation of the meninges (the membranes that enclose the brain and spinal cord) without evidence of a bacterial infection, which is unusual and made a quick diagnosis difficult, says a report from Japan. The man…
Vaccination against SARS-CoV-2, the virus that causes COVID-19, may trigger neuromyelitis optica spectrum disorder (NMOSD), a case report suggests. The report, “Antibody‐Positive Neuromyelitis Optica Spectrum Disorder After Second COVID‐19 Vaccination: a Case Report,” was published in the journal SN Comprehensive Clinical Medicine. Recommended…
The use of immunomodulatory therapy based on type 1 interferons (IFNs) may trigger neuromyelitis optica spectrum disorder (NMOSD), according to a new case report. Researchers in China described the case of a 24-year-old man diagnosed with the autoimmune disease after receiving treatment with IFN-alpha, a…
Giving immunosuppressive therapy to patients with antibodies against aquaporin-4 protein (AQP4) and optic neuritis but no symptoms may help resolve observed lesions and prevent a relapse of neuromyelitis optica spectrum disorder (NMOSD), a case report suggests. The case study, “Radiologically isolated aquaporin-4 antibody neuromyelitis optica spectrum disorder,” was…
A case report has detailed the clinical journeys of two identical twin sisters’ simultaneous diagnosis with neuromyelitis optica spectrum disorder (NMOSD), a rare occurrence. NMOSD was last reported in identical twin sisters in 1938, but those girls’ symptoms started two years apart, unlike the present case. The case report,…
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