brain lesions

A history of smoking is associated with poorer recovery from disease relapses in people with neuromyelitis optica spectrum disorder (NMOSD), a study reports. Findings indicate that patients who smoke or are past smokers are more likely to have neurological lesions that persist months after the relapse, and that these…

The presence of lesions in the brain’s middle medulla, a control center for breathing, increases the likelihood of acute respiratory failure in people with neuromyelitis optica spectrum disorder (NMOSD), a study suggests. While middle medullary lesions on MRI were the key predictor of acute respiratory failure in patients with…

Brain and spinal cord lesions resolve less often in children with neuromyelitis optica spectrum disorder (NMOSD) than with myelin oligodendrocyte glycoprotein antibody disease (MOGAD), a related disorder, according to a small study. No significant differences in resolving lesions were seen between children with NMOSD and those with multiple…

My mom was incredibly angry with me, and rightfully so, the day I lost my retainer. We fed four kids on one income, yet somehow afforded braces and then a retainer, which I was supposed to wear all the time except when eating. I remember playing with the retainer in…

Asymptomatic, or “silent,” MRI lesions are not common during disease remission in patients with aquaporin-4 antibody neuromyelitis optica spectrum disorder (AQP4-NMOSD) and myelin oligodendrocyte glycoprotein antibody disease (MOGAD), but are associated with imminent relapse when they do occur, according to a recent U.K. study. “Results of…

Treatment with Horizon Therapeutics’ Uplizna (inebilizumab) leads to a rapid and sustained drop in immune B-cells in adults with neuromyelitis optica spectrum disorder (NMOSD), data from the N-MOmentum Phase 2/3 clinical trial show. Notably, while all Uplizna-treated patients experienced significant clinical benefits, those with greater B-cell depletion showed lower…