News

Being positive for or showing high levels of antibodies against the aquaporin-4 (AQP4) protein at diagnosis doesn’t predict worse outcomes for people with neuromyelitis optica spectrum disorder (NMOSD), according to a small study. Plasma exchange therapy was linked with a trend for slower disability progression, although it wasn’t…

People with neuromyelitis optica spectrum disorder (NMOSD) have increased levels in the cerebrospinal fluid (CSF) — the liquid surrounding the brain and spinal cord — of three inflammatory biomarkers, a new study shows. The elevated concentrations of these biomarkers — YKL-40, sCD163, and sCD14 — also…

A chemotherapy regimen was able to treat a woman’s neuromyelitis optica spectrum disorder (NMOSD) which was likely secondary to follicular lymphoma, a type of cancer that begins in cells of the immune system, according to a case report by researchers at King’s College London in the U.K. O-CVP —…

Among people with neuromyelitis optica spectrum disorder (NMOSD) who started treatment with Uplizna (inebilizumab-cdon) in a clinical trial, an early and strong reduction in B-cell counts was associated with a quicker decline in disease activity. This report comes from an analysis of data from the Phase 2/3…

Researchers have identified a rare case of co-existing neuromyelitis optica spectrum disorder (NMOSD) and subacute combined degeneration (SCD) — two distinct disorders marked by nerve damage in the brain or spinal cord. The case highlights the possibility that NMOSD may be the underlying driver of the vitamin B12 deficiency…

Women are more likely to have neuromyelitis optica spectrum disorder (NMOSD) symptoms, or a rebound of symptoms, within three months after delivering a baby, a Chinese study found. Women who didn’t receive immunotherapy during pregnancy and the postpartum period were more than five times as likely to have…

A 67-year-old man developed a rare case of neuromyelitis optica spectrum disorder (NMOSD) after his third dose of the COVID-19 vaccine, a study reports. A review of published literature showed this case adds to 15 other reported cases of post-COVID-19 vaccination NMOSD onset, which appear to show similar clinical…

Adults with neuromyelitis optica spectrum disease (NMOSD) who are positive for antibodies against the aquaporin-4 (AQP4) protein have a higher prevalence of oval-shaped masses surrounding the optic nerve in their eyes than healthy people, a study showed. Although these masses were significantly linked to older age, their occurrence was…

A young woman had a rebound of neuromyelitis optica spectrum disorder (NMOSD) toward the end of her pregnancy, for which she underwent plasma exchange and took steroids, according to a report from researchers in the U.S. Because treatment with plasma exchange and steroids did not work well enough, the…

Certain variations in the ESR1 gene — a protein-coding gene for estrogen receptor-alpha — are significantly more common among women with neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis (MS) than among healthy women, a small study suggests. Such differences were not observed between men with these…